Human recombinant NMNAT3 (highly active) (from E. coli)

Toimittaja: ProSci Inc.

90-356
PRSI90-356EA 448 EUR
PRSI90-356
Human recombinant NMNAT3 (highly active) (from E. coli)
Proteiinit

Mitochondrial NMNAT isoform. Catalyses the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form of nicotinic acid mononucleotide (NAMN) as substrate with the same efficiency. Can use tiazofurin monophosphate as substrate. Can also use GTP and ITP as nucleotide donors. Also catalyses the reverse reaction, i. e. the pyrophosphorolytic cleavage of NAD+. For the pyrophosphorolytic activity, mitochondrial NMNAT isoform can use NAD(+), NADH, NAAD, nicotinic acid adenine dinucleotide phosphate (NHD), nicotinamide guanine dinucleotide (NGD) as substrates. Fails to cleave phosphorylated dinucleotides NADP+, NADPH and NAADP+. Protects against axonal degeneration following injury.


Fusion-Tag: His Tag


This recombinant proteins is for research use only.

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