Anti-LAG3 Mouse Monoclonal Antibody (Biotin)

Toimittaja: ENZO LIFE SCIENCES
ALX804806BC100
ENZOALX804806BC100EA 744 EUR
ENZOALX804806BC100
Anti-LAG3 Mouse Monoclonal Antibody (Biotin)
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The lymphocyte activation gene-3 (LAG-3, CD223), a member of the immunoglobulin superfamily (IgSF) related to CD4, binds to the major histocompatibility complex (MHC) class II molecules but with higher affinity than CD4. Several alternative mRNA splice-variants of human LAG-3 have been described, two of them encoding potential secreted forms: LAG-3V1 (i.e. the D1-D2 domains of the protein, 36 kDa) and LAG-3V3 (D1-D3, 52 kDa). The longer form was detected by ELISA in the serum of healthy individuals as well as of tuberculosis patients with a favorable outcome. LAG-3 expression by T cellMore Product Information
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