Rocaglamide ≥98% (by HPLC)

Toimittaja: ENZO LIFE SCIENCES

ALX350121C100
ENZOALX350121C100EA 646 EUR
ENZOALX350121C100
Rocaglamide ≥98% (by HPLC)
Rocaglamide

NF-kappaB inhibitor


Immunosuppressant. Potent inhibitor of NF-kappaB activation in T cells, with an almost complete inhibition at 200nM. Suppresses cytokine production (IFN-gamma, TNF-alpha, IL-2 and IL-4) and inhibits NF-AT in peripheral blood T cells at concentrations that do not impair NF-kappaB and AP-1 activities. In contrast to the immunosuppressant cyclosporin A (Prod. No. BML-A195), rocaglamide does not inhibit calcineurin phosphatase activity. Induces apoptosis.


Isolated from Aglaia sp.

Kaava: C₂₉H₃₁NO₇
MDL numero: MFCD08702699
CAS-numero: 84573-16-0

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