Anti-Presenilin 1 Rabbit Polyclonal Antibody

Toimittaja: Biosensis
R-1605-500
BSENR-1605-500EA 321 EUR
BSENR-1605-500
Anti-Presenilin 1 Rabbit Polyclonal Antibody
Vasta-aineet
Presenilin-1 (PSEN1) is a multi-pass membrane protein and component of the gamma-secretase complex. PSEN1 is thought to play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. It may also play a role in hematopoiesis. Defects in PSEN1 are a cause of Alzheimer disease type 3 (AD3), a familial early-onset form of Alzheimer disease (Ref:SWISS-Prot).

Specificity confirmed by WB and IF using transfected cells, Presenilin 1 knock-out mouse cells, mouse and human brain.
Application Information:
IF and WB. Suggested dilution of 1:2,000 isMore Product Information
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