Anti-KRIT1 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Toimittaja: Bioss
BS-8546R-A350
BOSSBS-8546R-A350EA 893 EUR
BOSSBS-8546R-A350
Anti-KRIT1 Rabbit Polyclonal Antibody (Alexa Fluor® 350)
Vasta-aineet
Component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity (By similarity). Negative regulator of angiogenesis. Inhibits endothelial proliferation, apoptosis, migration, lumen formation and sprouting angiogenesis in primary endothelial cells. Promotes AKT phosphorylation in a NOTCH-dependent and independent manner, and inhibits ERK1/2 phosphorylation indirectly through activation of the DELTA-NOTCH cascade. Acts in concert with CDH5 to establish and maintain correct endothelial cell polarity and vascular lumen and these effects areMore Product Information
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