Anti-BUB1 Rabbit Polyclonal Antibody (Cy5®)

Toimittaja: Bioss
BS-4294R-CY5
BOSSBS-4294R-CY5EA 900 EUR
BOSSBS-4294R-CY5
Anti-BUB1 Rabbit Polyclonal Antibody (Cy5®)
Vasta-aineet
Serine/threonine-protein kinase that performs 2 crucial functions during mitosis: it is essential for spindle-assembly checkpoint signaling and for correct chromosome alignment. Has a key role in the assembly of checkpoint proteins at the kinetochore, being required for the subsequent localization of CENPF, BUB1B, CENPE and MAD2L1. Required for the kinetochore localization of PLK1. Plays an important role in defining SGOL1 localization and thereby affects sister chromatid cohesion. Acts as a substrate for anaphase-promoting complex or cyclosome (APC/C) in complex with its activator CDH1 (APC/More Product Information
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