Anti-HPV33 E7 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Toimittaja: Bioss
BS-2969R-A350
BOSSBS-2969R-A350EA 893 EUR
BOSSBS-2969R-A350
Anti-HPV33 E7 Rabbit Polyclonal Antibody (Alexa Fluor® 350)
Vasta-aineet
E7 protein has both transforming and trans-activating activities. Disrupts the function of host retinoblastoma protein RB1/pRb, which is a key regulator of the cell cycle. Induces the disassembly of the E2F1 transcription factors from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Inactivation of the ability of RB1 to arrest the cell cycle is critical for cellular transformation, uncontrolled cellular growth and proliferation induced by viral infection. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNAMore Product Information
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