Anti-Cyclin D2 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Toimittaja: Bioss
BS-1148R-A750
BOSSBS-1148R-A750EA 899 EUR
BOSSBS-1148R-A750
Anti-Cyclin D2 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Vasta-aineet
Regulatory component of the cyclin D2-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also substrate for SMAD3,More Product Information
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