Anti-MSH2 Rabbit Polyclonal Antibody (Cy7®)

Toimittaja: Bioss
BS-0758R-CY7
BOSSBS-0758R-CY7EA 900 EUR
BOSSBS-0758R-CY7
Anti-MSH2 Rabbit Polyclonal Antibody (Cy7®)
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Component of the post-replicative DNA mismatch repair system (MMR). Forms two different heterodimers: MutS alpha (MSH2-MSH6 heterodimer) and MutS beta (MSH2-MSH3 heterodimer) which binds to DNA mismatches thereby initiating DNA repair. When bound, heterodimers bend the DNA helix and shields approximately 20 base pairs. MutS alpha recognizes single base mismatches and dinucleotide insertion-deletion loops (IDL) in the DNA. MutS beta recognizes larger insertion-deletion loops up to 13 nucleotides long. After mismatch binding, MutS alpha or beta forms a ternary complex with the MutL alphaMore Product Information
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