Anti-CD59 Mouse Monoclonal Antibody (CF594) [clone: BRA-10G]

Toimittaja: Biotium
BNC940181-500 BNC940181-100
BNC940181-500EA 560 EUR
BNC940181-500 BNC940181-100
Anti-CD59 Mouse Monoclonal Antibody (CF594) [clone: BRA-10G]
Vasta-aineet
Reacts with human CD59, a 20 kDa glycosyl phosphatidyl-inositol (GPI)-anchored cell surface protein. CD59 regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. CD59 is widely distributed on cells in all tissues. It inhibits formation of MAC, thus protecting cells fromMore Product Information
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