Anti-ICAM3 Mouse Monoclonal Antibody (CF647) [clone: 101-1D2]

Toimittaja: Biotium
BNC470177-500 BNC470177-100
BNC470177-500EA 560 EUR
BNC470177-500 BNC470177-100
Anti-ICAM3 Mouse Monoclonal Antibody (CF647) [clone: 101-1D2]
Vasta-aineet
Recognizes an N-glycosylated glycoprotein of 120 kDa with intra-chain disulfide bonds, identified as CD50 or ICAM-3 (WS: IV & V). Its epitope localizes in the D2 extracellular domain and is resistant to neuraminidase and proteases. CD50 is the major ligand for LFA-1 (CD11a/CD18) and may have signalling role to increase adhesion. It is expressed on thymocytes and T lymphocytes and is resistant to treatment with phosphatidylinositol (PI) phospholipase C. This MAb inhibits primary mixed lymphocyte culture (MLC) but not secondary MLC, cytotoxicity or proliferation induced by mitogens. ItMore Product Information
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