Anti-GNS Rabbit Polyclonal Antibody (Cy7®)

Toimittaja: Bioss
BS-13479R-CY7
BOSSBS-13479R-CY7EA 900 EUR
BOSSBS-13479R-CY7
Anti-GNS Rabbit Polyclonal Antibody (Cy7®)
Vasta-aineet
GNS is a 552 amino acid lysosomal enzyme that hydrolyzes the 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate and heparan sulfate. A member of the sulfatase family, GNS assists in the catabolism of heparin, and binds calcium as a cofactor. GNS deficiency results in an autosomal recessive lysosomal storage disorder known as mucopolysaccharidosis type IIID (Sanfilippo D syndrome), which is characterized by mild somatic disease and severe degeneration of the central nervous system. Subject to post-translational internal peptidase cleavage, GNS is encoded by aMore Product Information
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